synergistic effect — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TQ0211	Brusatol	(+)-Brusatol,NSC 172924	Others , Ferroptosis , Nrf2
	Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.		Others , Ferroptosis , Nrf2
T4763	Trans-Cyclohexane-1,2-diol	trans-1,2-Cyclohexanediol	Others , Endogenous Metabolite
	trans-Cyclohexane-1,2-diol (trans-1,2-Cyclohexanediol) has a synergistic retardation effect on percutaneous absorption and penetration of metronidazole (MTZ).		Others , Endogenous Metabolite
T26168	Rufigallol	AI3 00865,AI3-00865,AI300865
	Rufigallol (AI3-00865) is an electron-deficient disk-shaped molecule with six hydroxyl groups and is a good unit for inducing the formation of DLC from non-planar AIE molecules, an anthraquinone derivative.Rufigallol ind...
TN3700	Corianin		Others
	Corianin and coriatin demonstrate synergistic effect to insecticidal activity of tutin againstarmyworm.		Others
T70373	AS2575959
	AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.
TN3701	Coriatin		Others
	Coriatin and corianin demonstrate synergistic effect to insecticidal activity of tutin againstarmyworm.		Others
T27052	CMP3a	CMP-3a,CMP 3a
	CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destab...
T30831	Cgp 43182	Cgp-43182,Cgp43182
	CGP 43182 is an effective inhibitor of group IIA secretory phospholipase A2 (Group IIA sPLA2) activity in vitro, which can be used to prevent the synergistic effect of pro-inflammatory genes stimulated by cytokines media...
T79264	Z1078601926
	Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].
T74318	18:0 EPC chloride
	18:0 EPC chloride, a synthetic cationic phospholipid, significantly enhances eugenol's inactivation effect on Escherichia coli [1] when used at critical synergistic concentrations ranging from 2.34 to 2.93 μM.
T69935	L0909
	L0909 is an orally available inhibitors of Hepatitis C virus with a novel mechanism of action (EC50 = 0.022 μM, SI > 600). L0909 could block HCV replication by acting on the HCV entry stage. The high sensitivity to clini...
T61751	DNA-PK-IN-3
	DNA-PK-IN-3 is a highly potent inhibitor of DNA-PK. This compound exerts a synergistic effect when combined with radiotherapy and chemotherapy, resulting in enhanced therapeutic outcomes and significant inhibition of tum...
T76325	GHRF, bovine
	Bovine Growth Hormone-Releasing Factor (bGRF(1-44)-NH2), commonly referred to as bovine GHRF, is a compound that stimulates the release of bovine growth hormone (GH). It has been found to exhibit a synergistic effect whe...
T75485	Dehydrobruceine B
	Dehydrobruceine B, a quassinoid isolated from Brucea javanica, demonstrates a synergistic effect with Cisplatin in inducing apoptosis through the mitochondrial pathway. It enhances the expression of apoptosis-inducing fa...
T71361	CHS-828 nicotinate
	CHS-828 nicotinate is a CHS-828 salt with Nicotinic acid.. CHS-828 also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting ...
T69162	Ki23057
	Ki23057 is a a FGFR2 inhibitor, which enhances the chemosensitivity of drug-resistant gastric cancer cell lines when used in combination with chemotherapeutic drugs. Ki23057 might be therapeutically promising for treatin...
TN4470	Lyoniside		Antifection
	Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes, they demonstrate strong anti-leishmanial efficacies in BALB/c mice model of leishmaniasis, suggests that these two compounds potentia...		Antifection
T62234	JAK3/BTK-IN-3
	JAK3/BTK-IN-3 is a potent inhibitor of JAK3/BTK. BTK and JAK3 are two important targets in autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway has a synergistic effect and JAK3/BTK-IN-3 has sh...
T62153	JAK3/BTK-IN-5
	JAK3/BTK-IN-5 is a potent inhibitor of JAK3/BTK. where BTK and JAK3 are two key targets in autoimmune diseases. Simultaneous inhibition of the BTK/JAK3 signalling pathway has a synergistic effect and JAK3/BTK-IN-5 has po...
TN1690	Glabrene		Others , Estrogen/progestogen Receptor , Tyrosinase
	Glabrene, Liquiritin apioside, neolicuroside, and 18α²-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely the major contributors to the notable synergistic antioxidan...		Others , Estrogen/progestogen Receptor , Tyrosinase